An important substance found naturally in the skin as a structural component to fortify the epidermis' first line of defense - also known as our protection barrier - against sensitizing agents and external stress factors, as well as reducing moisture loss from skin surface. It is a fatty acid that functions as the "glue" that holds cells together for a tight cellular junction, promoting a healthy and intact skin barrier with microbiomes in balance.

However, improper use of cosmetics, changes in weather, aging...etc will lead to a depletion of ceramides, and hence a disrupted protection barrier that is susceptible to dryness, irritation, and bacterial infection. Studies have also shown that people with eczema have less ceramides than usual, making it a necessity for those with eczema to incorporate ceramides into their skin care routine for a positive prognosis of the condition.