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"What Really Ages Your Skin? A Deep Dive from Epidermis to Mitochondria"

New and Promising Discovery 

Mitochondria is where ATP also known as cellular energy is produced, so it’s essentially a powerplant responsible for fuelling all kinds of renewal processes in the skin such as keratinocytes, melanocytes, collagen synthesis…etc. Therefore, without ATP, a lot of cellular processes slow down. With natural aging, cumulation of DNA mutation, sun exposure, excessive free radical damage..etc your mitochondrial activity can slow down or become dysfunctional. 

With many studies supporting the essential role of skin aging attributed to declining mitochondrial function, scientists are exploring ways mitochondrial health can be enhanced. There are also well-proven ingredients that support mitochondrial function, and they are provided in the list below: 

Ingredient

Function

Remarks

Widely proven: 

Vitamin C

Scavenges free radicals that affect mitochondria health; promotes collagen synthesis

Effective at 10-20%; ~2 times potency when paired with Ferulic Acid and Vitamin E

Vitamin B3

Boosts ATP production, reduces inflammation and oxidative stress

Effective at 2-5%

Coenzyme Q10

Restores APT generation, repairs free radical damage

Effective at 0.3-1%

Resveratrol 

Boosts mitochondrial biogenesis and reduces oxidative stress

Effective at 0.3-2%

Retinol 

Upiregulates key mitochondrial proteins and reduces oxidative damage

Effective at 0.1-0.5%

Newer discoveries:

Methylene Blue

A mitochondrial targeting antioxidant

Some cases of irritation; for sensitive skin or those with G6PD deficiency use with care; not recommended for use during pregnancy

 

[Explore Skin Need mitochondrial supporting formulas]

Aging is the body’s natural process and while one makes the best effort in preserving wellness to prolong our health-span, it is essential to keep a positive mindset to embrace what is natural and inevitable.